Chitin synthase inhibitor 6

Chitin synthase inhibitor 6

• CAS Number: 3033645-29-0
• UNSPSC Description: Chitin synthase inhibitor 6 (compound 9b) is a potent chitin synthase (CHS) inhibitor with an IC50 value of 0.21 mM. Chitin synthase inhibitor 6 has broad-spectrum antifungal activity against drug-resistant fungi. Chitin synthase inhibitor 6 can be used in the research of fungi infection[1].
• Target Antigen: Fungal
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/chitin-synthase-inhibitor-6.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NC1=CC=C(OC)C=C1)/C=C/C(N2CCC3(CC2)C4=CC(OC)=CC=C4NC(O3)=O)=O
• Molecular Weight: 451.47
• References & Citations: [1]Xu Y, et, al. Spiro[benzoxazine-piperidin]-one derivatives as chitin synthase inhibitors and antifungal agents: Design, synthesis and biological evaluation. Eur J Med Chem. 2022 Aug 31;243:114723.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported