Chitin synthase inhibitor 14

Chitin synthase inhibitor 14

• CAS Number: 2922114-19-8
• UNSPSC Description: Chitin synthase inhibitor 14 (compound 4n) is chitin synthase (CHS) inhibitor. Chitin synthase inhibitor 14 has antifungal activity while possessed the potency against drug-resistant fungal variants[1].
• Target Antigen: Fungal
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/chitin-synthase-inhibitor-14.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C2(CCCN2C(CN3CCN(C(C4=C(Cl)C=CC([N+]([O-])=O)=C4)=O)CC3)=O)CC5=CC=CC=C5N1
• Molecular Weight: 511.96
• References & Citations: [1]Liu L, et al. Novel spiro[pyrrolidine-2,3'-quinoline]-2'-one derivatives containing piperazine fragment as potential chitin synthase inhibitors and antifungal agents: Design, synthesis and biological evaluation. Eur J Med Chem. 2023 Nov 15;260:115777.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported