Chitin synthase inhibitor 13

• UNSPSC Description:

  Chitin synthase inhibitor 13 (compound 12g) is a non-competitive inhibitor of chitin synthase, with an IC50 of 106.7 μM. Chitin synthase inhibitor 13 exhibits a broad-spectrum of antifungal activity[1].

• Target Antigen:

  Fungal

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/chitin-synthase-inhibitor-13.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC1=CC=C([N+]([O-])=O)C=C1)/C=C/C(NC2=CC3=C(NC4(CSCC4)NC3=O)C=C2)=O

• Molecular Weight:

  453.47

• References & Citations:

  [1]Du C, et, al. Design, synthesis and biological evaluation of novel spiro-quinazolinone derivatives as chitin synthase inhibitors and antifungal agents. Eur J Med Chem. 2023 Jul 5;255:115388.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2925228-79-9