hMAO-B/MB-COMT-IN-2

• UNSPSC Description:

  hMAO-B/MB-COMT-IN-2 is a dual MAO-B/MB-COMT inhibitor (IC50s: 4.27 μΜ for hMAO-B, 2.69 μΜ for MB-COMT). hMAO-B/MB-COMT-IN-2 protects cells against oxidative damage. hMAO-B/MB-COMT-IN-2 can be used in the research of neurodegeneration disease, such as Parkinson’s Disease (PD)[1].

• Target Antigen:

  COMT; Monoamine Oxidase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease;Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/hmao-b-mb-comt-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC1=CC(/C=C/C=C(C#N)\C(N2CCCCC2)=O)=CC=C1O

• Molecular Weight:

  298.34

• References & Citations:

  [1]Daniel Chavarria, et al. Boosting caffeic acid performance as antioxidant and monoamine oxidase B/catechol-O-methyltransferase inhibitor. Eur J Med Chem. 2022 Sep 8;243:114740.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3033106-46-3