hMAO-B/MB-COMT-IN-2

hMAO-B/MB-COMT-IN-2

• CAS Number: 3033106-46-3
• UNSPSC Description: hMAO-B/MB-COMT-IN-2 is a dual MAO-B/MB-COMT inhibitor (IC50s: 4.27 μΜ for hMAO-B, 2.69 μΜ for MB-COMT). hMAO-B/MB-COMT-IN-2 protects cells against oxidative damage. hMAO-B/MB-COMT-IN-2 can be used in the research of neurodegeneration disease, such as Parkinson’s Disease (PD)[1].
• Target Antigen: COMT; Monoamine Oxidase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease;Neuronal Signaling
• Applications: Neuroscience-Neurodegeneration
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/hmao-b-mb-comt-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: OC1=CC(/C=C/C=C(C#N)\C(N2CCCCC2)=O)=CC=C1O
• Molecular Weight: 298.34
• References & Citations: [1]Daniel Chavarria, et al. Boosting caffeic acid performance as antioxidant and monoamine oxidase B/catechol-O-methyltransferase inhibitor. Eur J Med Chem. 2022 Sep 8;243:114740.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported