hMAO-B-IN-3
CAT:
804-HY-143499
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
hMAO-B-IN-3
- CAS Number: 2581113-51-9
- UNSPSC Description: hMAO-B-IN-3 (Compound 15) is a potent inhibitor of hMAO-B with an IC50 of 47.4 nM. hMAO-B-IN-3 is playing favourable agent-like properties and a broad safety window. hMAO-B-IN-3 is thus a suitable candidate for lead optimization and the development of multitarget-directed ligands[1].
- Target Antigen: Monoamine Oxidase
- Type: Reference compound
- Related Pathways: Neuronal Signaling
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/hmao-b-in-3.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(OCC1=CC=CC=C1)/C(C#N)=C/C=C/C2=CC=C(OCO3)C3=C2
- Molecular Weight: 333.34
- References & Citations: [1]Chavarria D, et al. Design of novel monoamine oxidase-B inhibitors based on piperine scaffold: Structure-activity-toxicity, drug-likeness and efflux transport studies. Eur J Med Chem. 2020 Jan 1;185:111770.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported