hMAO-B-IN-2
CAT:
804-HY-146691
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

hMAO-B-IN-2
- CAS Number: 2454459-87-9
- UNSPSC Description: hMAO-B-IN-2 (compound 6j) is an orally active, potent, selective and BBB penetrated and competitive reversible hMAO-B inhibitor, with an IC50 of 4 nM. hMAO-B-IN-2 shows low toxicity and good neuroprotective effects in SH-SY5Y cell. hMAO-B-IN-2 can be used for alzheimer’s disease research[1]. hMAO-B-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Target Antigen: Monoamine Oxidase
- Type: Reference compound
- Related Pathways: Neuronal Signaling
- Applications: Neuroscience-Neurodegeneration
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/hmao-b-in-2.html
- Solubility: 10 mM in DMSO
- Smiles: C#CCN(CCCCCOC1=CC2=C(C(CCO2)=O)C=C1)C
- Molecular Weight: 301.38
- References & Citations: [1]Xie SS, Liu J, Tang C, et al. Design, synthesis and biological evaluation of rasagiline-clorgyline hybrids as novel dual inhibitors of monoamine oxidase-B and amyloid-β aggregation against Alzheimer's disease. Eur J Med Chem. 2020;202:112475.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported