hMAO-B-IN-6

hMAO-B-IN-6

• CAS Number: 2764830-43-3
• UNSPSC Description: hMAO-B-IN-6 (compound 17d) is a potent and selective inhibitor of hMAO-B with an IC50 of 67.02 nM. hMAO-B-IN-6 significantly improves Scopolamine (HY-N0296)-induced cognitive impairment in AD mice[1].
• Target Antigen: Monoamine Oxidase
• Type: Reference compound
• Related Pathways: Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/hmao-b-in-6.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C(O)=C(C)N(CCNCC2=COC3=C(C=CC(OC)=C3)C2=O)C=C1
• Molecular Weight: 356.37
• References & Citations: [1]Zhang C, et al. Chromone-based monoamine oxidase B inhibitor with potential iron-chelating activity for the treatment of Alzheimer's disease. J Enzyme Inhib Med Chem. 2023 Dec;38(1):100-117.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported