ICy-OH

• UNSPSC Description:

  ICy-OH, an iodinated photosensitizer, is an effective anticancer agent. ICy-OH can be used not only for deep tissue imaging (λex=640 nm，λem=690-740 nm) but also to selectively induce cell death in pancreatic cancer cells via cell pyroptosis pathway[1].

• Target Antigen:

  Pyroptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;Immunology/Inflammation

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/icy-oh.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC1=CC2=C(C=C1)C=C3CCCC(/C=C/C4=[N+](C)C5=C(C=C(I)C=C5)C4(C)C)=C3O2.[I-]

• Molecular Weight:

  637.29

• References & Citations:

  [1]Bo Peng, et al. NQO-1 Enzyme-Activated NIR Theranostic Agent for Pancreatic Cancer. Anal Chem. 2022 Aug

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2863682-80-6