ICy-OH

• Description :

  ICy-OH, an iodinated photosensitizer, is an effective anticancer agent. ICy-OH can be used not only for deep tissue imaging (λex=640 nm, λem=690-740 nm) but also to selectively induce cell death in pancreatic cancer cells via cell pyroptosis pathway[1].

• UNSPSC :

  12352005

• Target :

  Pyroptosis

• Type :

  Reference compound

• Related Pathways :

  Apoptosis; Immunology/Inflammation

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/icy-oh.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OC1=CC2=C(C=C1)C=C3CCCC(/C=C/C4=[N+](C)C5=C(C=C(I)C=C5)C4(C)C)=C3O2.[I-]

• Molecular Formula :

  C26H25I2NO2

• Molecular Weight :

  637.29

• References & Citations :

  [1]Bo Peng, et al. NQO-1 Enzyme-Activated NIR Theranostic Agent for Pancreatic Cancer. Anal Chem. 2022 Aug

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2863682-80-6]