Anticancer agent 76

• Description:

  Anticancer agent 76 (Compound CT2-3) is an anticancer agent. Anticancer agent 76 significantly inhibits the proliferation of human NSCLC cells, induces cell cycle arrest, causes ROS generation and induces cell apoptosis[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis; c-Myc; ROS Kinase; Topoisomerase

• Type:

  Reference compound

• Related Pathways:

  Apoptosis; Cell Cycle/DNA Damage; Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/anticancer-agent-76.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1N(CCCCS(CCOC2=CC=C(CC=C)C=C2C3=CC(CC=C)=CC=C3O)=O)C(C4=C1C=CC=C4)=O

• Molecular Formula:

  C32H33NO5S

• Molecular Weight:

  543.67

• References & Citations:

  [1]Chen J, et al. CT2-3, a novel magnolol analogue suppresses NSCLC cells through triggering cell cycle arrest and apoptosis. Bioorg Med Chem. 2020 Mar 15;28 (6) :115352.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2448091-11-8]