Anticancer agent 105

• Description :

  Anticancer agent 105 is a compound based on thienopyrimidine scaffold, with with good safety and anticancer properties. Anticancer agent 105 shows selective toxicity towards melanoma cancer, and induces apoptosis. And Anticancer agent 105 significantly inhibits the metastatic nodules, even in pulmonary metastatic melanoma mouse model[1].

• CAS Number :

  [2450987-57-0]

• UNSPSC :

  12352005

• Target :

  Apoptosis

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/anticancer-agent-105.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(OCC)C1=C(NC(/C(O[K])=C(C(N)=O)\C#N)=C\C(C2=CC=C(OC)C=C2)=O)SC3=C1CCCC3

• Molecular Formula :

  C25H24KN3O6S

• Molecular Weight :

  533.64

• References & Citations :

  [1]Rogova A, et al. Synthesis of thieno[3,2-e]pyrrolo[1,2-a]pyrimidine derivatives and their precursors containing 2-aminothiophenes fragments as anticancer agents for therapy of pulmonary metastatic melanoma. Eur J Med Chem. 2023 Jun 5;254:115325.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported