PAP-IN-2

• UNSPSC Description:

  PAP-IN-2 (Compound 35) is a purple acid phosphatase (PAP) inhibitor (Kis: 186 nM). PAP-IN-2 can be used for development of anti-osteoporotic compounds[1].

• Target Antigen:

  Phosphatase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/pap-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(CCCCCCCCCCCCCCCCC)NC(P(O)(O)=O)C1=CC=C(OC)C=C1

• Molecular Weight:

  483.62

• References & Citations:

  [1]Feder D, et al. Optimization of an α-aminonaphthylmethylphosphonic acid inhibitor of purple acid phosphatase using rational structure-based design approaches. Eur J Med Chem. 2023 Jun 5;254:115383.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported