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PAP-IN-1

CAT: 0804-HY-149942Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149942Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PAP-IN-1 (compound 28) is an inhibitor of purple acid phosphatases (PAPs), a ubiquitous binuclear metallohydrolase. PAP-IN-1 inhibits mammalian PAP with Ki value of 168 nM. PAP-IN-1 targets to pig PAP with Kic value of 0.17 μM. PAP inhibitors can be used for research of anti-osteoporotic drugs[1].
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pap-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(CCCCCCCCCCCCCCCCC)NC(P(O)(O)=O)C1=CC=CC=C1
Molecular Formula
C25H44NO4P
Molecular Weight
453.59
References & Citations
[1]Feder D, et al. Optimization of an α-aminonaphthylmethylphosphonic acid inhibitor of purple acid phosphatase using rational structure-based design approaches. Eur J Med Chem. 2023 Jun 5;254:115383.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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