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AKT-IN-18

CAT: 0804-HY-149842Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149842Size:1 Each
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Description
AKT-IN-18, an inhibitor of Akt, inhibits Akt with an IC50 of 69.45 μΜ in A549 cells. AKT-IN-18 induces apoptosis and can be used in non-small cell lung cancer study[1].
UNSPSC
12352005
Target
Akt; Apoptosis
Type
Reference compound
Related Pathways
Apoptosis; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/akt-in-18.html
Solubility
10 mM in DMSO
Smiles
O=C(N/N=C/C1=CC=C(N2C=CN=C2)C=C1)CSC3=NC4=CC(Cl)=CC=C4O3
Molecular Formula
C19H14ClN5O2S
Molecular Weight
411.86
References & Citations
[1]Erdönmez B, et.al. Design, Synthesis, and Evaluation of a New Series of Hydrazones as Small-Molecule Akt Inhibitors for NSCLC Therapy. ACS Omega. 2023 May 24;8 (22) :20056-20065.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Akt

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