β2AR agonist 2

CAT: 0804-HY-149727Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-149727Size:1 Each
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Description
β2AR agonist 2 (compound 8a) is a β2 -Adrenergic receptor (β2AR) agonist. β2AR agonist 2 is a saturated nitrogen ring compound containing 4- to 7-membered heterocycle. β2AR agonist 2 has a chiral structure (the -R form) by carrying carbon containing the essential hydroxyl, thereby enhancing cellular glucose uptake (GU) activity and significantly stimulating glucose uptake by skeletal muscle cells. β2AR agonist 2 can be used in the study of Type 2 Diabetes (T2D) [1].
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/β2ar-agonist-2.html
Solubility
10 mM in DMSO
Smiles
FC1=CC=CC([C@@H](O)[C@@]2([H])C[C@@H](CCC)N2)=C1
Molecular Formula
C13H18FNO
Molecular Weight
223.29
References & Citations
[1]Jaunsleine K, et al. Development of novel β2-adrenergic receptor agonists for the stimulation of glucose uptake - The importance of chirality and ring size of cyclic amines. Bioorg Med Chem Lett. 2023 Nov 13:129562.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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