β2AR agonist 2

• UNSPSC Description:

  β2AR agonist 2(compound 8a) is a β2 -Adrenergic receptor (β2AR) agonist. β2AR agonist 2 is a saturated nitrogen ring compound containing 4- to 7-membered heterocycle. β2AR agonist 2 has a chiral structure (the -R form) by carrying carbon containing the essential hydroxyl, thereby enhancing cellular glucose uptake (GU) activity and significantly stimulating glucose uptake by skeletal muscle cells. β2AR agonist 2 can be used in the study of Type 2 Diabetes (T2D)[1].

• Target Antigen:

  Adrenergic Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/β2ar-agonist-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  FC1=CC=CC([C@@H](O)[C@@]2([H])C[C@@H](CCC)N2)=C1

• Molecular Weight:

  223.29

• References & Citations:

  [1]Jaunsleine K, et al. Development of novel β2-adrenergic receptor agonists for the stimulation of glucose uptake - The importance of chirality and ring size of cyclic amines. Bioorg Med Chem Lett. 2023 Nov 13:129562.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported