β2AR/M-receptor agonist-1

• UNSPSC Description:

  β2AR/M-receptor agonist-1 (example 131) is a muscarinic antagonist and β2 adrenoceptor agonist (MABA). β2AR/M-receptor agonist-1 shows potency to β2 adrenoceptor with an EC50 value of 9.2 nM. β2AR/M-receptor agonist-1 also has potency to muscarinic receptor with a Ki value of 30.2 nM. β2AR/M-receptor agonist-1 shows MABA potency with an EC50 value of 4.0 nM[1].

• Target Antigen:

  Adrenergic Receptor; mAChR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/β2ar-m-receptor-agonist-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@@H](C1=C2C(NC(C=C2)=O)=C(C=C1)O)CNCCCOC(C=C3)=CC=C3OCCC[N+]45C[C@H](C(CC5)CC4)OC[C@@](C6CCCC6)(C7=CC=CC=C7)O.[Br-]

• Molecular Weight:

  806.82

• References & Citations:

  [1]WEN SHOUMING, et al. CLASS OF BIFUNCTIONAL COMPOUNDS WITH QUATERNARY AMMONIUM SALT STRUCTURE. WO2018108089. 2018.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2230520-62-2