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D4R agonist-1

CAT: 0804-HY-149481-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-149481-01Size:1 mg
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Description
D4R agonist-1 (Compound 16f) is a D4R partial agonist (Ki: 2.2 nM) . D4R agonist-1 is metabolically stable in rat and human liver microsomes. D4R agonist-1 can be used for research of neuropsychiatric disorders[1].
CAS Number
2826198-44-9
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/d4r-agonist-1.html
Solubility
10 mM in DMSO
Smiles
C12=CC=CC=C1N=C(S2)CCCN3CCN(CC3)C4=NC=CC=C4
Molecular Formula
C19H22N4S
Molecular Weight
338.47
References & Citations
[1]Boateng CA, et al. Pharmacology and Therapeutic Potential of Benzothiazole Analogues for Cocaine Use Disorder. J Med Chem. 2023 Aug 30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported