Squalene synthase-IN-1

• UNSPSC Description:

  Squalene synthase-IN-1 (compound 1) is a potent antihyperlipidemic agent acting through Squalene Synthase inhibition. Squalene synthase-IN-1 exhibits an outstanding antioxidant and anti-inflammatory activity. Squalene synthase-IN-1 displays a significant reduction not only of glucose but also of oxidative stress levels, while it did not cause any toxicity[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/squalene-synthase-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CN1CCOC(O)(C2=CC=C(NC(C=CC=C3)=C3S4)C4=C2)C1.Br

• Molecular Weight:

  395.31

• References & Citations:

  [1]Matralis AN, et al. Effect of a new squalene synthase inhibitor on an ApoE-/- mouse model of atherosclerosis. Bioorg Med Chem. 2023 Jul 15;90:117378.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported