Squalene synthase-IN-1

Squalene synthase-IN-1

• UNSPSC Description: Squalene synthase-IN-1 (compound 1) is a potent antihyperlipidemic agent acting through Squalene Synthase inhibition. Squalene synthase-IN-1 exhibits an outstanding antioxidant and anti-inflammatory activity. Squalene synthase-IN-1 displays a significant reduction not only of glucose but also of oxidative stress levels, while it did not cause any toxicity[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/squalene-synthase-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: CN1CCOC(O)(C2=CC=C(NC(C=CC=C3)=C3S4)C4=C2)C1.Br
• Molecular Weight: 395.31
• References & Citations: [1]Matralis AN, et al. Effect of a new squalene synthase inhibitor on an ApoE-/- mouse model of atherosclerosis. Bioorg Med Chem. 2023 Jul 15;90:117378.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported