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Squalene

CAT: 0804-HY-N1214-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N1214-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity[1][2].
CAS Number
111-02-4
Product Name Alternative
Super Squalene; trans-Squalene; AddaVax
UNSPSC
12352211
Hazard Statement
H304
Target
Endogenous Metabolite; Fungal; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Squalene.html
Purity
98.0
Solubility
DMSO : 16.67 mg/mL (ultrasonic) |Ethanol : 20 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C/C(C)=C\CC/C(C)=C/CC/C(C)=C/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)\C
Molecular Formula
C30H50
Molecular Weight
410.72
Precautions
H304
References & Citations
[1]Muzalevskaya EN, et al. SQUALENE: PHYSIOLOGICAL AND PHARMACOLOGICAL PROPERTIES. Eksp Klin Farmakol. 2015;78 (6) :30-6.|[2]Fernando Warleta, et al. Squalene protects against oxidative DNA damage in MCF10A human mammary epithelial cells but not in MCF7 and MDA-MB-231 human breast cancer cells. Food Chem Toxicol. 2010 Apr;48 (4) :1092-100. |[3]Clara Gabás-Rivera, et al. Dietary squalene increases high density lipoprotein-cholesterol and paraoxonase 1 and decreases oxidative stress in mice. PLoS One. 2014 Aug 12;9 (8) :e104224.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Human Endogenous Metabolite; Microbial Metabolite

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