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VEGFR2-IN-4

CAT: 0804-HY-149361Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149361Size:1 Each
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Description
VEGFR2-IN-4 (compound 25) is a potent and selective VEGFR2 kinase inhibitor, with a GI50 of 0.7 nM. VEGFR2-IN-4 shows anti-angiogenic effect. VEGFR2-IN-4 can be used for the research of rheumatoid arthritis[1].
CAS Number
3049398-38-8
UNSPSC
12352005
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/vegfr2-in-4.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(OC)=CC=C1)NC2=CC(SC3=CC=C4C(NN=C4NC(C)=O)=C3)=CC=C2
Molecular Formula
C23H20N4O3S
Molecular Weight
432.49
References & Citations
[1]Chen Q, et, al. Discovery of highly potent and selective VEGFR2 kinase inhibitors for the treatment of rheumatoid arthritis. Eur J Med Chem. 2023 Sep 5;257:115456.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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