Anticancer agent 131

CAT: 0804-HY-149327Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-149327Size:1 Each
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Description
HCT-116-IN-1, a γ-lactam-fused pyridone derivative, has anticancer activity and displayed high cytotoxicity against HCT116 cells with an IC50 of 5.59 μM[1].
CAS Number
[2864443-47-8]
UNSPSC
12352005
Target
Drug Derivative
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-131.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C(O)C(C2=C(C3=CC=C([N+]([O-])=O)C=C3)C(N(C4=CC=CC=C4)C5=C2CN(C6=C(C)C=CC=C6C)C5=O)=O)=C1
Molecular Formula
C33H24ClN3O5
Molecular Weight
578.01
References & Citations
[1]An YN, et.al. Unexpected Cascade Sequence Forming the C (sp3) -N/C (sp2) -C (sp2) Bond: Direct Access to γ-Lactam-Fused Pyridones with Anticancer Activity. J Org Chem. 2023 Jul 7;88 (13) :7998-8009.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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