HAA-09

• UNSPSC Description:

  HAA-09 is an orally active and potent anti-influenza agent, targeting the influenza PB2_cap binding domain. HAA-09 displays potent anti-influenza A virus activity, with an EC50 of 0.03 μM. HAA-09 shows polymerase inhibition, with an IC50 of 0.06±0.004 μM. HAA-09 blocks virus replication without causing obvious cytotoxicity[1].

• Target Antigen:

  Influenza Virus; Virus Protease

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/haa-09.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C)(N(NC1=C(C=NC(C2=CNC3=C2C=C(C=N3)F)=N1)F)CC(O)=O)C

• Molecular Weight:

  376.36

• References & Citations:

  [1]Wang S, et al. Synthesis and structure-activity optimization of 7-azaindoles containing aza-β-amino acids targeting the influenza PB2 subunit. Eur J Med Chem. 2023 Mar 15;250:115185.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1422051-33-9