HAA-09

• Description :

  HAA-09 is an orally active and potent anti-influenza agent, targeting the influenza PB2_cap binding domain. HAA-09 displays potent anti-influenza A virus activity, with an EC50 of 0.03 μM. HAA-09 shows polymerase inhibition, with an IC50 of 0.06±0.004 μM. HAA-09 blocks virus replication without causing obvious cytotoxicity[1].

• UNSPSC :

  12352005

• Target :

  Influenza Virus; Virus Protease

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/haa-09.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC(C)(N(NC1=C(C=NC(C2=CNC3=C2C=C(C=N3)F)=N1)F)CC(O)=O)C

• Molecular Formula :

  C17H18F2N6O2

• Molecular Weight :

  376.36

• References & Citations :

  [1]Wang S, et al. Synthesis and structure-activity optimization of 7-azaindoles containing aza-β-amino acids targeting the influenza PB2 subunit. Eur J Med Chem. 2023 Mar 15;250:115185.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1422051-33-9]