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Antipsychotic agent-2

CAT: 0804-HY-149247Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149247Size:1 Each
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Description
Antipsychotic agent-2 (Compound 11) is a potent antipsychotic agent. Antipsychotic agent-2 shows affinities for 5-HT1A, 5-HT2A, 5-HT2C, D2 and H1 receptors with Kis of 56.6, 66.7, 552, 596 and 1140 nM, respectively. Antipsychotic agent-2 has BBB permeability[1].
CAS Number
9007-83-4
UNSPSC
12352005
Target
5-HT Receptor; Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/antipsychotic-agent-2.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NNC2=CC=CC=C21)NCCCCN3CCN(CC3)C4=CC=C(C=C4)F
Molecular Formula
C22H26FN5O
Molecular Weight
395.47
References & Citations
[1]Stępnicki P, et al. Discovery of novel arylpiperazine-based DA/5-HT modulators as potential antipsychotic agents - Design, synthesis, structural studies and pharmacological profiling. Eur J Med Chem. 2023 Apr 5;252:115285.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor;5-HT2 Receptor; D2 Receptor; mLAG-3; α-1 microglobulin

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