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PDE5-IN-5

CAT: 0804-HY-147990Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147990Size:1 Each
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Description
PDE5-IN-5 (Compound 11) is a potent, selective phosphodiesterase 5 (PDE5) inhibitor with an IC50 of 2.0 nM[1].
CAS Number
2414921-33-6
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pde5-in-5.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CCN(C1)C([C@@]2([H])CC3=C([C@@H](C4=CC=C(Br)C=C4)N2C1=O)NC5=C3C=CC=C5)=O
Molecular Formula
C23H20BrN3O4
Molecular Weight
482.33
References & Citations
[1]ElHady AK, et al. Extending the use of tadalafil scaffold: Development of novel selective phosphodiesterase 5 inhibitors and histone deacetylase inhibitors. Bioorg Chem. 2020 May;98:103742.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE5

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