PDE5-IN-5

PDE5-IN-5

• CAS Number: 2414921-33-6
• UNSPSC Description: PDE5-IN-5 (Compound 11) is a potent, selective phosphodiesterase 5 (PDE5) inhibitor with an IC50 of 2.0 nM[1].
• Target Antigen: Phosphodiesterase (PDE)
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pde5-in-5.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(O)CCN(C1)C([C@@]2([H])CC3=C([C@@H](C4=CC=C(Br)C=C4)N2C1=O)NC5=C3C=CC=C5)=O
• Molecular Weight: 482.33
• References & Citations: [1]ElHady AK, et al. Extending the use of tadalafil scaffold: Development of novel selective phosphodiesterase 5 inhibitors and histone deacetylase inhibitors. Bioorg Chem. 2020 May;98:103742.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported