PDE5-IN-5

• Description :

  PDE5-IN-5 (Compound 11) is a potent, selective phosphodiesterase 5 (PDE5) inhibitor with an IC50 of 2.0 nM[1].

• UNSPSC :

  12352005

• Target :

  Phosphodiesterase (PDE)

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/pde5-in-5.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(O)CCN(C1)C([C@@]2([H])CC3=C([C@@H](C4=CC=C(Br)C=C4)N2C1=O)NC5=C3C=CC=C5)=O

• Molecular Formula :

  C23H20BrN3O4

• Molecular Weight :

  482.33

• References & Citations :

  [1]ElHady AK, et al. Extending the use of tadalafil scaffold: Development of novel selective phosphodiesterase 5 inhibitors and histone deacetylase inhibitors. Bioorg Chem. 2020 May;98:103742.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  PDE5

• CAS Number :

  [2414921-33-6]