Antitubercular agent-27

• Description :

  Antitubercular agent-27 (compound 1) is a potent antitubercular agent with an IC50 value of 3.2 μM, an MIC value of 7.8 μM, an IC90 value of 7.0 μM. Antitubercular agent-27 shows antimycobacterial activity for resistant isolates of Mycobacterium tuberculosis H37Rv. Antitubercular agent-27 shows effective intracellular antimycobacterial activity and low cytotoxicity[1].

• CAS Number :

  [2460651-09-4]

• UNSPSC :

  12352005

• Target :

  Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/antitubercular-agent-27.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(NN(C(C1=C2C=CC=C1Br)=O)C2=O)C3=CC=NC=C3

• Molecular Formula :

  C14H8BrN3O3

• Molecular Weight :

  346.14

• References & Citations :

  [1]Patel H, et al. Synthesis and in vitro antitubercular activity of pyridine analouges against the resistant Mycobacterium tuberculosis. Bioorg Chem. 2020 Sep;102:104099.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported