Antibacterial agent 111

• Description:

  Antibacterial agent 111 (Compound 3) is an antibacterial agent with MIC values of 3.90 μg/mL and 0.49 μg/mL against B. cereus and K. pneumonia, respectively. Antibacterial agent 111 firmly binds with tyrosyl-tRNA synthetase residues[1].

• UNSPSC:

  12352005

• Target:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antibacterial-agent-111.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N#CC1=C (C2=CC=CC=C2) C3=C (N (C4=NC=CC=N4) C (C) =N3) NC1=S

• Molecular Formula:

  C18H12N6S

• Molecular Weight:

  344.39

• References & Citations:

  [1]Othman IMM, et al. Design, synthesis ADMET and molecular docking of new imidazo[4,5-b]pyridine-5-thione derivatives as potential tyrosyl-tRNA synthetase inhibitors. Bioorg Chem. 2020 Sep;102:104105.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2448358-84-5