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Antibacterial agent 110

CAT: 0804-HY-147866Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147866Size:1 Each
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Description
Antibacterial agent 110 (Compound 4e) is a potent antibacterial agent with a MIC value of 1 μg/mL against P. aeruginosa. Antibacterial agent 110 possesses favorable antibiofilm activity and can destroy cell membranes. Antibacterial agent 110 causes metabolic arrest and intracellular oxidative stress, and obstructs DNA replication[1].
CAS Number
9007-83-4
UNSPSC
12352005
Target
Bacterial; DNA/RNA Synthesis; ROS Kinase
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Protein Tyrosine Kinase/RTK
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-110.html
Solubility
10 mM in DMSO
Smiles
CN1C=CN=C1SCC(CN2C(/C(C3=C2C=CC=C3)=N\NC4=CC=C(C=C4)C(O)=O)=O)O
Molecular Formula
C22H21N5O4S
Molecular Weight
451.50
References & Citations
[1]Li FF, et al. Discovery of novel phenylhydrazone-based oxindole-thiolazoles as potent antibacterial agents toward Pseudomonas aeruginosa. Eur J Med Chem. 2022 Jun 9;239:114521.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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