Antibacterial agent 110

• UNSPSC Description:

  Antibacterial agent 110 (Compound 4e) is a potent antibacterial agent with a MIC value of 1 μg/mL against P. aeruginosa. Antibacterial agent 110 possesses favorable antibiofilm activity and can destroy cell membranes. Antibacterial agent 110 causes metabolic arrest and intracellular oxidative stress, and obstructs DNA replication[1].

• Target Antigen:

  Bacterial; DNA/RNA Synthesis; ROS Kinase

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Cell Cycle/DNA Damage;Protein Tyrosine Kinase/RTK

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antibacterial-agent-110.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CN1C=CN=C1SCC(CN2C(/C(C3=C2C=CC=C3)=N\NC4=CC=C(C=C4)C(O)=O)=O)O

• Molecular Weight:

  451.50

• References & Citations:

  [1]Li FF, et al. Discovery of novel phenylhydrazone-based oxindole-thiolazoles as potent antibacterial agents toward Pseudomonas aeruginosa. Eur J Med Chem. 2022 Jun 9;239:114521.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4