CB1-IN-2

• Description:

  CB1-IN-2 (Compound 4g) is a selective CB1 inhibitor with an IC50 of 0.644 μM. CB1-IN-2 can penetrates BBB and might cause CNS side effect similar with Rimonabant[1].

• UNSPSC:

  12352005

• Target:

  Cannabinoid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/cb1-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=NN(C2=CC=C(Cl)C=C2Cl)C(C3CC3)=N1)NN4CCCCC4

• Molecular Formula:

  C17H19Cl2N5O

• Molecular Weight:

  380.27

• References & Citations:

  [1]Tsai SE, et al. Chlorotrimethylsilane promoted one-flask heterocyclic synthesis of 1,2,4-triazoles from nitrilimines: Modeling studies and bioactivity evaluation of LH-21 and Rimonabant analogues. Bioorg Chem. 2020 Nov;104:104299.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CB1

• CAS Number:

  [2527805-39-4]