CB1-IN-2

• Description :

  CB1-IN-2 (Compound 4g) is a selective CB1 inhibitor with an IC50 of 0.644 μM. CB1-IN-2 can penetrates BBB and might cause CNS side effect similar with Rimonabant[1].

• UNSPSC :

  12352005

• Target :

  Cannabinoid Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/cb1-in-2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=NN(C2=CC=C(Cl)C=C2Cl)C(C3CC3)=N1)NN4CCCCC4

• Molecular Formula :

  C17H19Cl2N5O

• Molecular Weight :

  380.27

• References & Citations :

  [1]Tsai SE, et al. Chlorotrimethylsilane promoted one-flask heterocyclic synthesis of 1,2,4-triazoles from nitrilimines: Modeling studies and bioactivity evaluation of LH-21 and Rimonabant analogues. Bioorg Chem. 2020 Nov;104:104299.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  CB1

• CAS Number :

  [2527805-39-4]