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Anticancer agent 70

CAT: 0804-HY-147816Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147816Size:1 Each
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Description
Anticancer agent 70 (Compound 21), an anticancer agent, exhibits remarkable cytotoxic activity against numerous human cancer cell lines. Anticancer agent 70 results in the G0/G1-cell cycle arrest with a concomitant increase in p53 and p21 protein levels. Anticancer agent 70 leads to ATP depletion and disruption of the mitochondrial membrane potential[1].
CAS Number
2521770-35-2
UNSPSC
12352005
Target
Mitochondrial Metabolism
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-70.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(Cl)C=C1Cl)(NC2=CC=CC3=C2NN=C3)=O
Molecular Formula
C13H9Cl2N3O2S
Molecular Weight
342.20
References & Citations
[1]Bułakowska A, et al. Novel N- (aryl/heteroaryl) -2-chlorobenzenesulfonamide derivatives: Synthesis and anticancer activity evaluation. Bioorg Chem. 2020 Nov;104:104309.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported