Anticancer agent 70

• Description :

  Anticancer agent 70 (Compound 21), an anticancer agent, exhibits remarkable cytotoxic activity against numerous human cancer cell lines. Anticancer agent 70 results in the G0/G1-cell cycle arrest with a concomitant increase in p53 and p21 protein levels. Anticancer agent 70 leads to ATP depletion and disruption of the mitochondrial membrane potential[1].

• UNSPSC :

  12352005

• Target :

  Mitochondrial Metabolism

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/anticancer-agent-70.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=S(C1=CC=C(Cl)C=C1Cl)(NC2=CC=CC3=C2NN=C3)=O

• Molecular Formula :

  C13H9Cl2N3O2S

• Molecular Weight :

  342.20

• References & Citations :

  [1]Bułakowska A, et al. Novel N- (aryl/heteroaryl) -2-chlorobenzenesulfonamide derivatives: Synthesis and anticancer activity evaluation. Bioorg Chem. 2020 Nov;104:104309.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2521770-35-2]