Anticancer agent 70

• UNSPSC Description:

  Anticancer agent 70 (Compound 21), an anticancer agent, exhibits remarkable cytotoxic activity against numerous human cancer cell lines. Anticancer agent 70 results in the G0/G1-cell cycle arrest with a concomitant increase in p53 and p21 protein levels. Anticancer agent 70 leads to ATP depletion and disruption of the mitochondrial membrane potential[1].

• Target Antigen:

  Mitochondrial Metabolism

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/anticancer-agent-70.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=S(C1=CC=C(Cl)C=C1Cl)(NC2=CC=CC3=C2NN=C3)=O

• Molecular Weight:

  342.20

• References & Citations:

  [1]Bułakowska A, et al. Novel N-(aryl/heteroaryl)-2-chlorobenzenesulfonamide derivatives: Synthesis and anticancer activity evaluation. Bioorg Chem. 2020 Nov;104:104309.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4