Anticancer agent 68

• UNSPSC Description:

  Anticancer agent 68 is (Compound 12) is an anti-cancer agent. Anticancer agent 68 arrests the cells at the G2/M phase and induces programmed cell death. Anticancer agent 68 induces upregulation of tumor suppression via activation of p53 & PTEN[1].

• Target Antigen:

  MDM-2/p53

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/anticancer-agent-68.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(OC)C1=C(C)C=C(OCC2=CC(C3=CC=C(Cl)C=C3)=NO2)C(C)=C1O

• Molecular Weight:

  387.81

• References & Citations:

  [1]Reddy ST, et al. Synthesis of some novel methyl β-orsellinate based 3, 5-disubstituted isoxazoles and their anti-proliferative activity: Identification of potent leads active against MCF-7 breast cancer cell. Bioorg Chem. 2020;105:104374.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4