DPPY

CAT: 0804-HY-147741Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-147741Size:1 Each
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Description
DPPY (compound 6) is a potent PTK inhibitor with IC50 values of [1].
CAS Number
[2095883-62-6]
UNSPSC
12352005
Target
Btk; EGFR; JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dppy.html
Solubility
10 mM in DMSO
Smiles
C=CC(NC1=CC(NC2=NC(NC3=CC=C(C=C3)NC(CN4CCOCC4)=O)=NC=C2Cl)=CC=C1)=O
Molecular Formula
C25H26ClN7O3
Molecular Weight
507.97
References & Citations
[1]Zhu Y, et al. Synthesis and biological activity of thieno[3,2-d]pyrimidines as potent JAK3 inhibitors for the treatment of idiopathic pulmonary fibrosis. Bioorg Med Chem. 2020 Jan 15;28 (2) :115254.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EGFR/ErbB1/HER1; JAK3

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Alternative Products

CatalogName
MBS5806154DPPY
MBS5806672Thi-DPPY
D8065-34DPP10 (Dipeptidyl peptidase 10, DPPY, DPRP3, DPL2) (Biotin)
479626DPP10 (DPPY Splice Variant d EMBL ABI16087.1, Dipeptidyl-Peptidase 10 (Non-Functional) )
MBS6007627-01Dipeptidyl Peptidase 10, aa521-539 (DPP10, DPL2, DPPY, DPRP-3, DPRP3, KIAA1492)
D8065-32FDipeptidyl Peptidase 10, aa521-539 (DPP10, DPL2, DPPY, DPRP-3, DPRP3, KIAA1492) discontinued. see D8065-32
170392DPP10 (Dipeptidyl Peptidase X, Dipeptidyl-Peptidase 10, DipeptidylPeptidase 10, DPL2, DPRP-3, DPRP3, Dipeptidyl Peptidase 10, DPPY, KIAA1492, DPP X)
170393DPP10 (Dipeptidyl Peptidase X, Dipeptidyl-Peptidase 10, DipeptidylPeptidase 10, DPL2, DPRP-3, DPRP3, Dipeptidyl Peptidase 10, DPPY, KIAA1492, DPP X) discontinued

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