DPPC

• Description:

  DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice[1][2][3][4][5].

• Product Name Alternative:

  129Y83

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H331, H336, H351, H361, H372, H412

• Target:

  Endogenous Metabolite; Liposome

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/DPPC.html

• Purity:

  99.91

• Solubility:

  DMSO : < 1 mg/mL|Ethanol : 25 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

• Smiles:

  CCCCCCCCCCCCCCCC(O[C@H](COC(CCCCCCCCCCCCCCC)=O)COP(OCC[N+](C)(C)C)([O-])=O)=O

• Molecular Formula:

  C40H80NO8P

• Molecular Weight:

  734.04

• Precautions:

  H302, H315, H319, H331, H336, H351, H361, H372, H412

• References & Citations:

  [1]Miller AD. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10 (6) :781-811.|[2]Akiko Uemura, et al. Induction of immune responses against glycosphingolipid antigens: comparison of antibody responses in mice immunized with antigen associated with liposomes prepared from various phospholipids. J Vet Med Sci. 2005 Dec;67 (12) :1197-201.|[3]Ege C, et al. Insertion of Alzheimer's A beta 40 peptide into lipid monolayers. Biophys J. 2004 Sep;87 (3) :1732-40.|[4]Kalra VK, et al. Transport of amino acids in gamma-glutamyl transpeptidase-implanted human erythrocytes. J Biol Chem. 1981 Jun 10;256 (11) :5567-71.|[5]Leekumjorn S, et al. Molecular simulation study of structural and dynamic properties of mixed DPPC/DPPE bilayers. Biophys J. 2006 Jun 1;90 (11) :3951-65.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Natural Products

• Clinical Information:

  Launched

• Isoform:

  Human Endogenous Metabolite; Microbial Metabolite

• CAS Number:

  [63-89-8]