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Thi-DPPY

CAT: 0931-T64008-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T64008-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2307699-34-7
Target
Others, JAK
Related Pathways
Chromatin/Epigenetic, Angiogenesis, Stem Cells, Others, JAK/STAT signaling, Tyrosine Kinase/Adaptors
Bioactivity
Thi-DPPY is a potent, orally active JAK3 inhibitor that acts on BTK (IC50: 62.4 nM), JAK (IC50: 1.38 nM) . Thi-DPPY is anti-proliferative against HBE cells. Thi-DPPY has anti-inflammatory effects in vivo. Thi-DPPY has shown research potential in idiopathic pulmonary fibrosis (IPF) .
Smiles
O(C1=C2C(=NC(NC3=CC(Cl)=C(OCCCN4CCOCC4)C=C3)=N1)C=CS2)C5=CC(NC(C=C)=O)=CC=C5
Molecular Formula
C28H28ClN5O4S
Molecular Weight
566.07
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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