Thi-DPPY

• CAS Number :

  2307699-34-7

• Target :

  Others|||JAK

• Related Pathways :

  Chromatin/Epigenetic|||Angiogenesis|||Stem Cells|||Others|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

• Bioactivity :

  Thi-DPPY is a potent, orally active JAK3 inhibitor that acts on BTK (IC50: 62.4 nM), JAK (IC50: 1.38 nM) . Thi-DPPY is anti-proliferative against HBE cells. Thi-DPPY has anti-inflammatory effects in vivo. Thi-DPPY has shown research potential in idiopathic pulmonary fibrosis (IPF) .

• Smiles :

  O(C1=C2C(=NC(NC3=CC(Cl)=C(OCCCN4CCOCC4)C=C3)=N1)C=CS2)C5=CC(NC(C=C)=O)=CC=C5

• Molecular Formula :

  C28H28ClN5O4S

• Molecular Weight :

  566.07

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C