CB-5339

CAT: 0804-HY-128724-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-128724-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
CB-5339 is an oral activity potent p97 inhibitor with an IC50 [1]. CB-5339 extracted from WO2015109285A1 compound FF07.
CAS Number
[1863952-15-1]
UNSPSC
12352005
Target
P97
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cb-5339.html
Purity
99.58
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O=C(C1=CC=CC2=C1C=C(C)N2C3=NC(NCC4=CC=CC=C4)=C(CCCN5)C5=N3)N
Molecular Formula
C24H24N6O
Molecular Weight
412.49
References & Citations
[1]David Wustrow, et al. FUSED PYRIMIDINES AS INHIBITORS OF p97 COMPLEX. WO2015109285A1.|[2]Roux B, et.al. Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor. Sci Transl Med. 2021 Mar 31;13 (587) :eabg1168.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1

Related Products

CatalogName
HY-16638CB 3717
HY-101863CB-6673567
HY-W717830CB-Cyclam
HY-120235CB-618
HY-12861-01CB-5083
HY-101862-01CB-7921220
HY-120360CB-64D
HY-122045CB 3705
HY-117001CB-7646
HY-147671CB 168

Alternative Products

CatalogName
MF-0036804-01CB-5339
M26091-01CB-6644
MBS826379-01CB-TH
MBS386727-01CB 300919
MBS3841841-01CB-1158
M14307-01CB-6673567
M11862-01CB-839
7379/25CB 5083
2663/50CB 65
7591/10CB 839

Popular Products