CB-6673567

• Description :

  CB-6673567 is a selective AC1 inhibitor with an IC50 of 77 μM .CB-6673567blocks the choline-induced cAMP increase and can be used for cardiovascular diseases research[1].

• UNSPSC :

  12352005

• Target :

  Adenylate Cyclase

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/cb-6673567.html

• Smiles :

  OC1=C2OCOC2=CC=C1C3=NNC=C3C4=CN(C5=CC=CC=C5)N=C4

• Molecular Formula :

  C19H14N4O3

• Molecular Weight :

  346.34

• References & Citations :

  [1]Brand CS, et al. Isoform selectivity of adenylyl cyclase inhibitors: characterization of known and novel compounds. J Pharmacol Exp Ther. 2013 Nov;347 (2) :265-75.|[2]Cheng Q, et al. Activation of α7 nicotinic acetylcholine receptors increases intracellular cAMP levels via activation of AC1 in hippocampal neurons. Neuropharmacology. 2015 Aug;95:405-14.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [379218-90-3]