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FGFR-IN-5

CAT: 0804-HY-147620Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147620Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FGFR-IN-5 is a potent inhibitor of FGFR. Fibroblast growth factor receptor (FGFR) is a tyrosine kinase receptor that binds to fibroblast growth factor ligands. FGFR-IN-5 has the potential for the research of cancer diseases (extracted from patent WO2022042612A1, compound 3) [1]. FGFR-IN-5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
2762750-70-7
UNSPSC
12352005
Target
FGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fgfr-in-5.html
Solubility
10 mM in DMSO
Smiles
C=CC(N1CC[C@@H](C1)N2C=C(C3=C2C(NN=C3N)=O)C#CC4=CC5=C(OC(C6CC6)=N5)C=C4)=O
Molecular Formula
C25H22N6O3
Molecular Weight
454.48
References & Citations
[1]Haibin Deng, et al. Dihydropyrrolo[2,3-d]pyridazin-7-one derivative, preparation method therefor, and application thereof. Patent WO2022042612A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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