FGFR-IN-2

• Description:

  FGFR-IN-2 (compound 1) is a potent FGFR inhibitor with IC50s of 7.3 nM, 4.3 nM, 7.6 nM, 11 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. FGFR-IN-2 has the potential for cancer research[1].

• UNSPSC:

  12352005

• Target:

  FGFR

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/fgfr-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CN1N=CC(C2=NN=C3C=CC(N(C4=CC(OC)=CC(OC)=C4)CCNC(C)C)=CC3=C2)=C1

• Molecular Formula:

  C25H30N6O2

• Molecular Weight:

  446.54

• References & Citations:

  [1]Don Zhang, et al. Pyridazine and 1,2,4-triazine derivatives as fgfr kinase inhibitors. WO2021146163A1.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2665665-09-6]