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FGFR-IN-2

CAT: 0804-HY-142921Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-142921Size:1 Each
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Description
FGFR-IN-2 (compound 1) is a potent FGFR inhibitor with IC50s of 7.3 nM, 4.3 nM, 7.6 nM, 11 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. FGFR-IN-2 has the potential for cancer research[1].
CAS Number
2665665-09-6
UNSPSC
12352005
Target
FGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fgfr-in-2.html
Solubility
10 mM in DMSO
Smiles
CN1N=CC(C2=NN=C3C=CC(N(C4=CC(OC)=CC(OC)=C4)CCNC(C)C)=CC3=C2)=C1
Molecular Formula
C25H30N6O2
Molecular Weight
446.54
References & Citations
[1]Don Zhang, et al. Pyridazine and 1,2,4-triazine derivatives as fgfr kinase inhibitors. WO2021146163A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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