CD73-IN-11

CAT: 0804-HY-147592Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-147592Size:1 Each
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Description
CD73-IN-11 is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-11 be used for preparing a medicament for tumor-related diseases (extracted from patent WO2022068929A1, compound 24) [1].
CAS Number
[2766566-11-2]
UNSPSC
12352005
Target
CD73
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cd73-in-11.html
Solubility
10 mM in DMSO
Smiles
O=C1NC=C(C(N1)=O)C2=NN3C(F)=CN=C3C([C@H]4C[C@@H]4C(F)F)=C2
Molecular Formula
C14H10F3N5O2
Molecular Weight
337.26
References & Citations
[1]Xuejun Zhang, et al. Pyrimidinedione compound and use thereof. Patent WO2022068929A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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