CD73-IN-11

• Description:

  CD73-IN-11 is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-11 be used for preparing a medicament for tumor-related diseases (extracted from patent WO2022068929A1, compound 24) [1].

• UNSPSC:

  12352005

• Target:

  CD73

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/cd73-in-11.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1NC=C(C(N1)=O)C2=NN3C(F)=CN=C3C([C@H]4C[C@@H]4C(F)F)=C2

• Molecular Formula:

  C14H10F3N5O2

• Molecular Weight:

  337.26

• References & Citations:

  [1]Xuejun Zhang, et al. Pyrimidinedione compound and use thereof. Patent WO2022068929A1.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2766566-11-2]