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CD73-IN-8

CAT: 0804-HY-147589Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-147589Size:1 Each
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Description
CD73-IN-8 is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-8 be used for preparing a medicament for tumor-related diseases (extracted from patent WO2022052886A1, compound 57) [1].
CAS Number
[2763710-08-1]
UNSPSC
12352005
Target
CD73
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cd73-in-8.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=O)NC=C1C2=NN=C(Cl)C([C@H]3C[C@@H]3C4=CC=CC=C4)=C2
Molecular Formula
C17H13ClN4O2
Molecular Weight
340.76
References & Citations
[1]Hao Wu, et al. Cd73 inhibitor and application thereof in medicine. Patent WO2022052886A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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