CD73-IN-8

• Description:

  CD73-IN-8 is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-8 be used for preparing a medicament for tumor-related diseases (extracted from patent WO2022052886A1, compound 57) [1].

• UNSPSC:

  12352005

• Target:

  CD73

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cd73-in-8.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC1=O)NC=C1C2=NN=C(Cl)C([C@H]3C[C@@H]3C4=CC=CC=C4)=C2

• Molecular Formula:

  C17H13ClN4O2

• Molecular Weight:

  340.76

• References & Citations:

  [1]Hao Wu, et al. Cd73 inhibitor and application thereof in medicine. Patent WO2022052886A1.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2763710-08-1]