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BTK-IN-14

CAT: 0804-HY-147584Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147584Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BTK-IN-14 is a potent inhibitor of BTK. BTK plays an important role in signaling mediated by B cell antigen receptor (BCR) and Fcγreceptor (FcγR) in B cells and myeloid cells, respectively. BTK-IN-14 has the potential for the research of related diseases, especially autoimmune diseases, inflammatory diseases or cancer (extracted from patent WO2022057894A1, compound 1) [1].
CAS Number
2764674-60-2
UNSPSC
12352005
Target
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/btk-in-14.html
Solubility
10 mM in DMSO
Smiles
C[C@H]1CN(C[C@@H](N1C2=CC=C(N=C2)NC3=CC(C4=CC=NC(N5C=CN6C(C5=O)=CC7=C6CC(C)(C7)C)=C4CO)=CN(C3=O)C)C)C8COC8
Molecular Formula
C38H44N8O4
Molecular Weight
676.81
References & Citations
[1] Guangxiu Dai, et al. Heteroaryl heterocyclic compounds and uses thereof. Patent WO2022057894A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported