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Antibacterial agent 107

CAT: 0804-HY-147546Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147546Size:1 Each
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Description
Antibacterial agent 107 (compound 14) is a potent antibacterial agent. Antibacterial agent 107 shows potent antibacterial activity against Gram-positive bacteria, with a MIC of 1.56 μg/mL (MRSA) . Antibacterial agent 107 exhibits low hemolytic activity, high membrane selectivity, and rapid bactericidal activity. Antibacterial agent 107 shows effective in vivo efficacy in the murine model of bacterial keratitis caused by Staphylococcus aureus ATCC29213[1].
CAS Number
2454636-44-1
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-107.html
Solubility
10 mM in DMSO
Smiles
C/C(C)=C\COC1=CC=C(C=C1)/C=C/C(C2=C(C=C(C=C2)OC/C=C(C)/C)OCC(N[C@H](C(N[C@H](C(N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)=O
Molecular Formula
C39H55N9O7
Molecular Weight
761.91
References & Citations
[1]Lin S, et al. Design, synthesis, and evaluation of amphiphilic sofalcone derivatives as potent Gram-positive antibacterial agents. Eur J Med Chem. 2020 Sep 15;202:112596.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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