RBP4 ligand-1

CAT: 0804-HY-147366Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-147366Size:1 Each
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Description
RBP4 ligand-1 is a non-retinoid ligands for (RBP4) retinol-binding protein 4. The hRBP4SPA IC50 and RBP4-TTR FRET IC50 values are 0.23±0.11 and 0.13±0.12 μM in the radioligand binding assay and FRET assay, respectively[1].
CAS Number
[260553-24-0]
UNSPSC
12352005
Target
Lipocalin Family
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/rbp4-ligand-1.html
Solubility
10 mM in DMSO
Smiles
FC(F)(C1=C(N2CCN(C(NC3=C(C=CC(Cl)=C3)OC)=O)CC2)N=CC=C1)F
Molecular Formula
C18H18ClF3N4O2
Molecular Weight
414.81
References & Citations
[1]Yingcai Wang, et al. Structure-assisted discovery of the first non-retinoid ligands for Retinol-Binding Protein 4. Bioorg Med Chem Lett. 2014 Jul 1;24 (13) :2885-91.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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