YTHDF2 ligand-1

• Description :

  YTHDF2 ligand-1 (Compound 23) is a selective and high-affinity YTHDF2 ligand with a Kd of 1.3 μM (FP assay) and an IC50 of 11 μM (HTRF assay) . YTHDF2 ligand-1 can be used in the study of cancer[1].

• UNSPSC :

  12352005

• Target :

  YTHDF

• Related Pathways :

  Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Purity :

  98.83

• Smiles :

  CC1=C(SC2=C1C(NC(N2)=S)=O)C(NCC3=CN=CC=C3)=O

• Molecular Formula :

  C14H12N4O2S2

• Molecular Weight :

  332.40

• References & Citations :

  [1]Invernizzi A, et al. Discovery of YTHDF2 ligands by fragment-based design. ACS Bio & Med Chem Au, 2025.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light, stored under nitrogen)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3093182-34-1]