RBP4 inhibitor 1

• UNSPSC Description:

  RBP4 inhibitor 1 (compound 43b) is a potent and orally active retinol-binding protein 4 (RBP4) inhibitor with IC50s of 28 nM and 110 nM for human and mouse RBP4. RBP4 inhibitor 1 has a potent and long-lasting blood RBP4-level-reducing effect in mice[1].

• Target Antigen:

  Lipocalin Family

• Type:

  Reference compound

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/rbp4-inhibitor-1.html

• Solubility:

  DMSO : 250 mg/mL (ultrasonic)

• Smiles:

  O=C(O)CO[C@@H]1CN(C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)CC1

• Molecular Weight:

  357.25

• References & Citations:

  [1]Shinji Nakamura, et al. Discovery of phenylpyrrolidine derivatives as a novel class of retinol binding protein 4 (RBP4) reducers. Bioorg Med Chem. 2022 Jan 15;54:116553.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  No Development Reported

• CAS Number:

  1198180-03-8