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Anticancer agent 42

CAT: 0804-HY-146516Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146516Size:1 Each
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Description
Anticancer agent 42 (compound 10d) is an orally active anticancer agent, and shows a potent antitumor activity against MDA-MB-231 cell with an IC50 of 0.07 μM. Anticancer agent 42 can exert its anticancer activity by activating apoptotic pathway and p53 expression. Anticancer agent 42 can be used to study metastatic breast cancer[1].
CAS Number
2687265-18-3
UNSPSC
12352005
Target
Apoptosis; MDM-2/p53; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-42.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C2=CC=CC=C2N1)C3=C(C(C(Cl)=C(C3=O)N4CCOCC4)=O)Cl
Molecular Formula
C19H16Cl2N2O3
Molecular Weight
391.25
References & Citations
[1]Jia J, Yin H, Chen C, et al. Design, synthesis, and evaluation of a novel series of mono-indolylbenzoquinones derivatives for the potential treatment of breast cancer. Eur J Med Chem. 2022 Apr 16;237:114375.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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