Anticancer agent 60

• Description :

  Anticancer agent 60 (compound 3h) has antiproliferative activity against human HepG2 cells (IC50 = 4.13 μM) and presents antitumor efficacy in a human HepG2 xenograft mouse model[1].

• CAS Number :

  [2162169-14-2]

• UNSPSC :

  12352005

• Target :

  Microtubule/Tubulin

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Cytoskeleton

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/anticancer-agent-60.html

• Solubility :

  10 mM in DMSO

• Smiles :

  COC1=NC(OC)=C(C=C1)N(S(=O)(C2=CC3=C(N(C4=C3C=CC=C4)C)C=C2)=O)CCN5CCN(CC5)C

• Molecular Formula :

  C27H33N5O4S

• Molecular Weight :

  523.65

• References & Citations :

  [1]Liu Y, et al. Synthesis and structure-activity relationship study of water-soluble carbazole sulfonamide derivatives as new anticancer agents. Eur J Med Chem. 2020;191:112181.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported