Anticancer agent 60

• UNSPSC Description:

  Anticancer agent 60 (compound 3h) has antiproliferative activity against human HepG2 cells (IC50 = 4.13 μM) and presents antitumor efficacy in a human HepG2 xenograft mouse model[1].

• Target Antigen:

  Microtubule/Tubulin

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Cytoskeleton

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/anticancer-agent-60.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=NC(OC)=C(C=C1)N(S(=O)(C2=CC3=C(N(C4=C3C=CC=C4)C)C=C2)=O)CCN5CCN(CC5)C

• Molecular Weight:

  523.65

• References & Citations:

  [1]Liu Y, et al. Synthesis and structure-activity relationship study of water-soluble carbazole sulfonamide derivatives as new anticancer agents. Eur J Med Chem. 2020;191:112181.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4