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Anticancer agent 50

CAT: 0804-HY-146389Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146389Size:1 Each
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Description
Anticancer agent 50 (compound 6) is a potent ABCB1 efflux pump modulator. Anticancer agent 50 shows cytotoxic effects and antiproliferative effects. Anticancer agent 50 decreases the expression of cyclin D1 and induces p53 expression. Anticancer agent 50 has the potential for the research of T-lymphoma[1].
CAS Number
2487457-15-6
UNSPSC
12352005
Target
MDM-2/p53; P-glycoprotein
Type
Reference compound
Related Pathways
Apoptosis; Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-50.html
Solubility
10 mM in DMSO
Smiles
COC(CN1C(N(C(C2=CC=CC=C2)(C1=O)C3=CC=CC=C3)CCCCCC[Se]C4=CC=CC=C4)=O)=O
Molecular Formula
C30H32N2O4Se
Molecular Weight
563.55
References & Citations
[1]Ali W, et al. Discovery of phenylselenoether-hydantoin hybrids as ABCB1 efflux pump modulating agents with cytotoxic and antiproliferative actions in resistant T-lymphoma. Eur J Med Chem. 2020 Aug 15;200:112435.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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