Tubulin polymerization-IN-19

• UNSPSC Description:

  Tubulin polymerization-IN-19 (compound 4) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-20 has the potential for the research of breast cancers and chemoresistant colon cancers[1].

• Target Antigen:

  Microtubule/Tubulin

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Cytoskeleton

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/tubulin-polymerization-in-19.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=CC(N2C([C@H]([C@@H]2C3=CC=C(C=C3)OC)C4=CC=CC=C4)=O)=CC(OC)=C1OC

• Molecular Weight:

  419.47

• References & Citations:

  [1]Malebari AM, et al. β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells. Eur J Med Chem. 2020;189:112050.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2340345-85-7