Antibacterial agent 95

• Description:

  The minimum inhibitory concentration (MIC) of a new 2- (quinoline-4-methoxy) acetamide antituberculotic agent against the reference strain of Mycobacterium tuberculosis H37Rv was as low as 0.3 μ M. It also inhibited the growth of Mycobacterium tuberculosis in the macrophage model of tuberculosis infection.

• UNSPSC:

  12352005

• Target:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antibacterial-agent-95.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=CC2=C(N=C(C=C2OCC(C3=CC=CC(Cl)=C3)=O)C)C=C1

• Molecular Formula:

  C19H16ClNO3

• Molecular Weight:

  341.79

• References & Citations:

  [1]Borsoi AF, et al. Design, synthesis, and evaluation of new 2- (quinoline-4-yloxy) acetamide-based antituberculosis agents. Eur J Med Chem. 2020 Apr 15;192:112179.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2413006-48-9