CI-39

• Description :

  CI-39 is an antiviral natural product. CI-39 is an NNRTI (non-nucleoside reverse transcriptase inhibit) antiviral agent with an EC50 of 3.40 μM and an CC50 of >30 μM for wild type HIV-1. CI-39 inhibits HIV-1 RT DNA polymerase and ribonuclease H activitiessup[1].

• UNSPSC :

  12352005

• Target :

  HIV

• Type :

  Natural Products

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/ci-39.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(CC1=CN(C2=C1C=CC=C2)OC)NC3=C(C(OC)=O)C=CC=C3

• Molecular Formula :

  C19H18N2O4

• Molecular Weight :

  338.36

• References & Citations :

  [1]Xu C, et al. Discovery, synthesis, and optimization of an N-alkoxy indolylacetamide against HIV-1 carrying NNRTI-resistant mutations from the Isatis indigotica root. Eur J Med Chem. 2020 Mar 1;189:112071.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  HIV-1

• CAS Number :

  [2132412-25-8]