Anticancer agent 48

• Description:

  Anticancer agent 48 (compound 48) is a broad spectrum anticancer agent. Anticancer agent 48 inhibits tubulin polymerization. Anticancer agent 48 shows antiproliferative activity. Anticancer agent 48 shows antitumor activity in vivo. Anticancer agent 48 has the potential for the research of solid and hematological tumors[1].

• UNSPSC:

  12352005

• Target:

  Microtubule/Tubulin

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage; Cytoskeleton

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/anticancer-agent-48.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=CC(C(C2=CN(C=C2C3=CC=C(C=C3)N)C4=CC=CC(N)=C4)=O)=CC(OC)=C1OC

• Molecular Formula:

  C26H25N3O4

• Molecular Weight:

  443.49

• References & Citations:

  [1]Puxeddu M, et al. Structure-activity relationship studies and in vitro and in vivo anticancer activity of novel 3-aroyl-1,4-diarylpyrroles against solid tumors and hematological malignancies. Eur J Med Chem. 2020 Jan 1;185:111828.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2395009-13-7]